vanilloid receptor antagonist 1 — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T9247	Vanilloid receptor antagonist 1	4-(7-Hydroxy-2-isopropyl-4-oxoquinazolin-3(4H)-yl)benzonitrile	TRP/TRPV Channel
	Vanilloid receptor antagonist 1 (4-(7-Hydroxy-2-isopropyl-4-oxoquinazolin-3(4H)-yl)benzonitrile) is a potent vanilloid receptor TRPV1 antagonist.		TRP/TRPV Channel
T29522	ABT 102	ABT102,CHEMBL398338,ABT-102	TRP/TRPV Channel
	ABT 102 (CHEMBL398338) is a selective antagonist of transient receptor potential vanilloid 1 (TRPV1) receptor.		TRP/TRPV Channel
T23322	SB 452533		TRP/TRPV Channel
	SB 452533 is an antagonist of the vanilloid receptor 1(pKb: 7.8).		TRP/TRPV Channel
T14087	ABT-239		TRP/TRPV Channel
	ABT-239 is a novel, highly efficacious antagonist belonging to the non-imidazole class of histamine H3 receptor (H3R) antagonists. It also acts as a transient receptor potential vanilloid type 1 (TRPV1) antagonist.		TRP/TRPV Channel
T7189	AMG9810		TRP/TRPV Channel
	AMG 9810 is a competitive antagonist of capsaicin activation of the vanilloid receptor 1 (TRPV1) (IC50s = 24.5 and 85.6 nM for human and rat TRPV1, respectively).		TRP/TRPV Channel
TN1377	α-Spinasterol	alpha-Spinasterol	COX , Antibacterial , TRP/TRPV Channel
	α-Spinasterol is a transient receptor potential vanilloid 1 (TRPV1) antagonist, has anti-inflammatory, antidepressant, antioxidant and antinociceptive effects. α-Spinasterol inhibits COX-1 andCOX-2 activities with IC50 v...		COX , Antibacterial , TRP/TRPV Channel
T10176	TRPV antagonist 1		Others
	TRPV antagonist 1 is an antagonist of transient receptor potential vanilloid (TRPV; IC50 < 250 nM).		Others
T26663	AS1928370
	AS1928370 is an antagonist of transient receptor potential vanilloid 1 (TRPV1).
T68256	JNJ-38893777
	JNJ-38893777 is a potent and selective transient receptor potential vanilloid 1 (TRPV1) channel antagonist.
T15439	GSK3395879		TRP/TRPV Channel
	GSK3395879 is a selective and orally bioavailable antagonist of transient receptor potential vanilloid-4 (TRPV4) (IC50: 1 nM for hTRPV4).		TRP/TRPV Channel
T37668	CAY10448	CAY10448
	Capsaicin is the primary active component of the heat and pain-eliciting lipid soluble fraction of the Capsicum pepper. Capsaicin signals are transduced by a heat-activated ion channel, the vanilloid receptor 1 (VR1), or...
T41091	JTS-653
	JTS-653 is a potent and selective in vitro and in vivo antagonist of transient receptor potential vanilloid 1 (TRPV1). It effectively attenuates chronic pain resistant to non-steroidal anti-inflammatory drugs.
T75830	L-R4W2 TFA
	L-R4W2 TFA acts as a potent antagonist of vanilloid receptor 1 (VR1, TRPV1), demonstrating significant inhibitory activity with an IC50 value of 0.1 μM. This compound potentially offers powerful analgesic properties [1] ...
T37321	RN-9893 (hydrochloride)
	RN-9893 is an antagonist of transient receptor potential vanilloid 4 (TRPV4; IC50s = 0.42 and 0.66 μM, respectively, for the human and rat receptors).1 It is selective for TRPV4 over TRPV1, TRPV3, and TRPM8 (IC50s = 10, ...
T37732	AMG 21629
	Potent and selective TRPV1 antagonist. Blocks Ca2+ uptake by CHO cells expressing TRPV1 receptors and acid-induced Ca2+ uptake, respectively). Exhibits >4000-fold selectivity for TRPV1 over other TRP channels. Blocks cap...
T83701	TRPV1-Tat TFA	Transient Receptor Potential Vanilloid 1-Tat,736-745-Tat
	TRPV1-Tat, a peptide antagonist targeting transient receptor potential vanilloid 1 (TRPV1), is composed of amino acids 736-745 derived from TRPV1's A-kinase anchor protein (AKAP)-binding domain, combined with the HIV Tat...